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Registration Dossier
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EC number: 923-835-0 | CAS number: -
Dissociation constant
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Administrative data
- Endpoint:
- dissociation constant
- Type of information:
- other: Measurement of individual dissociation constants of the UVCB substance is not possible
- Remarks:
- the UVCB substance is insoluble in water
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Principles of method if other than guideline:
- The column elution method was chosen for the determination of the hydrosolubility.Deviation : The first step of preliminary test was done at 23°C and not at 20°C
- The sand was washed only one time with acetone instead of two times These deviations were not considerated to have affected the quality or the interpretation of the result.
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
Results and discussion
- Dissociating properties:
- not determined
- Remarks:
- The hydrosolubility of LCE07100 is equal or lower than 1mg/L
Dissociation constant
- Remarks on result:
- not determinable
- Remarks:
- The hydrosolubility of LCE07100 is equal or lower than 1mg/L. the substance is an UVCB containing several ionisable components so measurement of individual dissociation constants using the complete UVCB is not possible. Furthermore, the substance is insoluble in water. Therefore this measurement is scientifically not possible: the test does not need to be proposed.
Applicant's summary and conclusion
- Conclusions:
- Considering REACH Annex IX 7.16 criteria, the dissociation constant should be determined. However the substance is an UVCB containing several ionisable components so measurement of individual dissociation constants using the complete UVCB is not possible. Furthermore, the substance is insoluble in water. Therefore this measurement is scientifically not possible: the test does not need to be proposed.
- Executive summary:
Considering REACH Annex IX 7.16 criteria, the dissociation constant should be determined. However the substance is an UVCB containing several ionisable components so measurement of individual dissociation constants using the complete UVCB is not possible. Furthermore, the substance is insoluble in water. Therefore this measurement is scientifically not possible: the test does not need to be proposed.
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