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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

The inhibition growth concentration (IGC50) value of phthalylsulfathiazole in microorganism (Tetrahymena pyriformis) for 48 hr study on the basis of effect on growth was estimated to be 25.10465 mg/L.

Key value for chemical safety assessment

EC50 or LC50 for microorganisms:
25.104 mg/L

Additional information

The inhibition growth concentration (IGC50) value of phthalylsulfathiazole in microorganism (Tetrahymena pyriformis) for 48 hr study on the basis of effect on growth was estimated to be 25.10465 mg/L. The pulblication study shows Minimum Inhibitory Concentration of substance phthalylsulfathiazole on microorganism at dose concentration of <=250ug/ml

Sr no

Endpoint Value Unit Species
 1  IGC50  25.10465  mg/l Tetrahymena pyriformis
2 MIC  <=250  ug/ml Escherichia coli ATCC 25922, LM1-Escherichia coli, LM2-Escherichia coli, Pseudomonasaeruginosa ATCC 27853 LM-Staphylococcus aureus, Staphylococcus aureus methicillin-sensitive ATCC 29213 and Staphylococcus aureus methicillin-resistant ATCC 43300