Registration Dossier
Registration Dossier
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EC number: 279-900-2 | CAS number: 82104-74-3
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- Bio-degradation in water by Environmental Science Center’s PBT profiler
- Author:
- Environmental Science Center
- Year:
- 2 010
- Bibliographic source:
- PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- PBT profiler database
- GLP compliance:
- no
Test material
- Reference substance name:
- 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile
- EC Number:
- 279-900-2
- EC Name:
- 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile
- Cas Number:
- 82104-74-3
- Molecular formula:
- C9H5NO2
- IUPAC Name:
- 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile
- Test material form:
- solid: crystalline
- Details on test material:
- - Name of test material: 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile
- Molecular formula: C9H5NO2
- Substance type: Organic
- Physical state: Solid
Constituent 1
Study design
- Oxygen conditions:
- other: modelling database
- Inoculum or test system:
- not specified
- Duration of test (contact time):
- 15 d
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- test mat. analysis
Results and discussion
% Degradation
- Parameter:
- other: half life
- Value:
- 50
- Sampling time:
- 15 d
- Remarks on result:
- other: 15 days = 360 hrs
- Details on results:
- Half life = 15 days
Any other information on results incl. tables
Media |
Half life (days) |
Percent in medium |
Water |
15 days |
24% |
Applicant's summary and conclusion
- Interpretation of results:
- readily biodegradable
- Conclusions:
- 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile is 50% biodegradable in water in 15 days (half-life) indicating 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile is readily biodegradable in water since the half life is less than the threshold of 60 days (to qualify the chemical as persistent)
- Executive summary:
1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile is 50% biodegradable in water in 15 days (half-life) indicating 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile is readily biodegradable in water since the half life is less than the threshold of 60 days (to qualify the chemical as persistent).
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