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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

No reliable studies were identified on the effects of furan on the skin or eyes; no studies have been entered into IUCLID.

Key value for chemical safety assessment

Additional information

Human Toxicity

A published review describing potential human effects notes that furan can “burn the skin and eyes” and that the vapour “can irritate the respiratory tract” (Pohanish, 2008).


The IARC monograph on furan notes that the occupational exposure limit for furan in the Russian Federation included a notation of skin irritancy (ILO, 1991).


Animal studies

A databank (HSDB, 2011) reports irritation when furan was applied at 1-50% to the skin of guinea pigs (Chernousov, 1974). No further details are given.


Chernousov AD (1974). [Allergenic properties of furan compounds.] Gig Sanit 6, 28-32 (as cited in HSDB, 2011).


HSDB (2011). Hazardous Substances Data Bank. Databank Number 89, last revised 16 June 2011.


ILO (1991). Occupational Exposure Limits for Airborne Toxic Substances: Values of Selected Countries. Occupational Safety and Health Series No. 37, 3rd Ed.,, p206-207 (as cited in WHO, 1995).


Pohanish, R.P (ed) (2008). Sittig’s Handbook of Toxic and Hazardous Chemical Carcinogens, 4th Edition Volume 1: A-H; p1194-1196.


WHO (1995). IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-present. Vol 63, 393-407.

Justification for classification or non-classification

Furan is classified Skin Irritation 2; H315: causes skin irritations (Regulation (EC) 1272/2008).

It is unclear from the data reported here how the current classification was derived.