Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February 2008 to august 2008
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
- The sand was washed only one time with acetone instead of two times as described in the corresponding procedure. - The pH of the collected fraction after the column elution was not taken. These dev
GLP compliance:
yes (incl. certificate)
Type of method:
column elution method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubility
Water solubility:
<= 1 mg/L
Temp.:
20 °C
Details on results:
The PH of the collected fraction after the column elution was not taken.

Any other information on results incl. tables

The PH of the collected fraction after the column elution was not taken.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The hydrosolubility of LCE07101 is equal or lower than 1 mg/L.
Executive summary:

As the preliminary test showed a hydrosolubility lower than 10mg/L, the column elution method was taken to determine the hydrosoolubility of LCE07101. The alcohols (C20 and C22), the main substances of LCE07101 were analysed as silyl derivates by gas chromatography using a FID detector. The limit of auqntification of the alcohols was 0.5 mg/L.

The analysis of the alcohols int he fractions obtained at elution flow rates of 12.5 and 25mL/h showed that the hydrosolubility of the alcohols is lower than 0.5 mg/L. The hydrosolubility of LCE07101 is equal or lower than 1 mg/L.