Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Lysozyme is naturally occurring in many organisms, including terrestrial organisms such as viruses, bacteria, plants, insects, birds, reptiles and mammals (Callewaert and Michiels, 2010), and therefore not expected to exhibit negative effects in the terrestrial environment.

Furthermore based on common industrial practice no releases are expected, thus direct and indirect exposure of the terrestrial compartment is unlikely and no specific test is necessary. Additionally, lysozyme is naturally present in the environment and in case releases occured they would be minimal in relation to natural background concentrations.

In general lysozyme can be regarded as the precursor of lysozyme hydrochloride; the transformation into the salt form does not significantly impact the toxicity potential for the organisms of the terrestrial compartment and it is expected that lysozyme and lysozyme hydrochloride share the same potential breakdown products via physical and biological process.


Callewaert L, and Michiels C W (2010). Lysozymes in the animal kingdom; J. Biosci. 35 127–160] DOI 10.1007/s12038-010-0015-5.