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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1983
Reference Type:
publication
Title:
1-Chlor-2-methyl-3-nitrobenzol (2-Chlor-6-nitrotoluol) BUA Stoffbericht 61
Author:
Beratergremium für umweltrelevante Altstoffe (BUA)
Year:
1991
Bibliographic source:
VCH Verlagsgesellschaft mbH, Weinheim, ISBN 3-527-28427-3

Materials and methods

Test guideline
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chloro-6-nitrotoluene
EC Number:
201-475-9
EC Name:
2-chloro-6-nitrotoluene
Cas Number:
83-42-1
Molecular formula:
C7H6ClNO2
IUPAC Name:
1-chloro-2-methyl-3-nitrobenzene

Test animals / tissue source

Species:
rabbit

Results and discussion

Any other information on results incl. tables

The examination of acute irritation / corrosion in the rabbit eye according to OECD Guideline 405 showed only minor irritation: slight iritis, mild swelling and distinct redness of the conjunctiva, low effluent. Corneal opacity or corneal lesions were not observed.

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU