Registration Dossier
Registration Dossier
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EC number: 201-475-9 | CAS number: 83-42-1
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- 1-Chlor-2-methyl-3-nitrobenzol (2-Chlor-6-nitrotoluol) BUA Stoffbericht 61
- Author:
- Beratergremium für umweltrelevante Altstoffe (BUA)
- Year:
- 1 991
- Bibliographic source:
- VCH Verlagsgesellschaft mbH, Weinheim, ISBN 3-527-28427-3
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 983
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 2-chloro-6-nitrotoluene
- EC Number:
- 201-475-9
- EC Name:
- 2-chloro-6-nitrotoluene
- Cas Number:
- 83-42-1
- Molecular formula:
- C7H6ClNO2
- IUPAC Name:
- 1-chloro-2-methyl-3-nitrobenzene
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- >= 2 000 mg/kg bw
Any other information on results incl. tables
With a single dermal application of 2000 mg / kg body weight of 2-chloro-6-nitrotoluene to the Wistar rat no signs of poisoning were observed, the pathology of the animals at the end of the post-observation period also showed no abnormalities.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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