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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
experimental study
Adequacy of study:
other information
Study period:
No data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: 2.g: Collection of data. Peer-review database

Data source

Referenceopen allclose all

Reference Type:
other: Peer-reviewed database
Title:
Data bank of environmental properties of chemicals
Author:
Kemikaali
Year:
2010
Bibliographic source:
http://wwwp.ymparisto.fi/scripts/Kemrek/Kemrek.asp, CAS n° 103-50-4, Finnish Environment Insitute
Reference Type:
other: Databank
Title:
Registry of Toxic Effects of Chemical Substances
Author:
RTECS
Year:
2010
Bibliographic source:
Centre Canadien d'hygiène et de sécurité au travail, CAS n° 140-29-4

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Phenylacetonitrile
EC Number:
205-410-5
EC Name:
Phenylacetonitrile
Cas Number:
140-29-4
Molecular formula:
C8H7N
IUPAC Name:
2-phenylacetonitrile
Details on test material:
No data

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
other: frog

Study design

Test type:
not specified
Water media type:
not specified
Remarks on exposure duration:
No data

Results and discussion

Effect concentrations
Dose descriptor:
other: LDLo
Effect conc.:
1 100 other: mg/kg
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The toxicity of phenylacetonitrile to frogs was tested by administering the substance subcutaneous. Under the test conditions, a LDLo of 1100 mg/kg was observed.
Executive summary:

The peer-reviewed databank reports that the toxicity of phenylacetonitrile (CAS n° 140-29-4) to frogs was tested when the test substance was administered subcutaneous. Under the reported conditions a LDLo was observed of 1100 mg/kg.