Registration Dossier
Registration Dossier
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EC number: 272-712-1 | CAS number: 68909-77-3 The residuum from the reaction of diethylene glycol and ammonia. It consists predominantly of morpholine-based derivatives such as [(aminoethoxy)ethyl]morpholine, [(hydroxyethoxy)ethyl]morpholine, 3-morpholinone, and 4,4'-(oxydi-2,1-ethanediyl)bis[morpholine].
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish:
In a static test following the procedures of the German national standard DIN 38412 using Leuciscus idus as test species a LC50 (96 h) of 681.2 mg/L (nominal) was determined [BASF AG, 1988; Study No. 10F0118/885140]. In conclusion, the substance is with high probability not acutely harmful to fish.
Short-term toxicity to aquatic invertebrates:
The EC50 of the test item on daphnids was found to be greater than 122 mg/L (measured value) in a GLP guideline study according to OECD 202 [BASF SE, 2010; Study No. 50E0396/09E012]. Therefore, the test substance is with high probability acutely not harmful to aquatic invertebrates.
Toxicity to aquatic algae and cyanobacteria:
No toxic effect were determined for "ethanol, 2,2'-oxybis-, reaction products with ammonia, morpholine derivs. residues" in the algae test. The 72-h ErC50 is > 120 mg/L (nominal). The 72 -h NOErC is >= 120 mg/L (nominal) [BASF SE, 2010; Study No. 60E0396/09E013]. In conclusion, the substance is with high probability acutely not harmful to algae.
Toxicity to microorganisms:
The toxicity to microorganisms was determined in a GLP short-term respiration test according to OECD guideline 209 using activated sludge from a municipal sewage treatment plant. After 180 minutes no inhibition effect on the respiration rate at the highest test concentration (1000 mg/L) was observed [BASF 2010; Study No. 08G0396/09G004]. Therefore, it can be concluded that inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
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