Registration Dossier

Administrative data

Description of key information

The recorded degradation products are titanium dioxide, propan-2-ol, triethanolamine and propylene glycol.  
These substances are not severely irritaitng to skin and eyes, altough propan-2-ol is classified as eye irritant.
Testing on similar titanates suggest low irritancy.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Justification for selection of skin irritation / corrosion endpoint:
Based on read-across to other titanates and assessment of degradation products

Justification for selection of eye irritation endpoint:
Based on read-across to other titanates and assessment of degradation products
Since propan-2-ol is perhaps the component most likely to lead to local irritation to eyes, titanium tetraisopropanoate (EC 208-909-6) and analogue substances have been reported for read-across. Some irritation was noted, but not sufficient for classification

Justification for classification or non-classification