Registration Dossier
Registration Dossier
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EC number: 275-069-5 | CAS number: 70969-58-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to aquatic algae: EC50 - > 6.9 mg/L; NOEC - 3.9 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 6.9 mg/L
- EC10 or NOEC for freshwater algae:
- 3.9 mg/L
Additional information
Algal growth inhibition has been investigated in a 72 hour test according to OECD/EU test methods.The EC50 values for inhibition of specific growth rate (ErC50) and yield (EyC50) was >6.9 mg/L. The NOEC for inhibition of specific growth rate (ErC0) and yield (EyC0) was 3.9 mg/L. In accordance with ECHA guidance on information requirements and chemical safety assessment, Chapter R.7b: Endpoint specific guidance, the ErC50 endpoint is used in DNEL derivation. This is because use of values based on biomass cannot be applied to an analysis of results from a system in exponential growth without logarithmic transformation.
(Q)SAR estimation indicates an EC50 of 0.418 mg/L, lower than the experimentally determined value.
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