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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Bioaccumulation: aquatic / sediment

Bioaccumulation study was conducted on test organism Cyprinus carpio for 6 weeks for evaluating the bioconcentration factor (BCF value) of test chemical (authoritative database, 2018). The study was performed according to other guideline"Bioaccumulation test of a chemical substance in fish or shellfish" provided in "the Notice on the Test Method Concerning New Chemical Substances", respectively under flow through conditions at a temperature of25°C and pH range 6.0-8.5, respectively. Cyprinus carpio(length - 8 dimensionless)was used as a test organism for the study.Test chemical nominal conc. used for the study were 0.5mg/l and 0.05 mg/l, respectively. Range finding study involve the TLm (48 hr) 160 mg/l (w/v) on Rice fish (Oryzias latipes). The bioconcentration factor (BCF value) of test chemical on Cyprinus carpio was determined to be in the range of 0.7-3.5 L/Kg at a conc. of 0.5 mg/l and ≤ 2.6 L/Kg at a conc. of 0.05 mg/l, respectively, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is not expected to bioaccumulate in the food chain.

Additional information

Bioaccumulation: aquatic / sediment

Experimental key study and various predicted data of the test chemical were reviewed for the bioaccumulation end point which are summarized as below:

 

In an experimental key study from authoritative databases (2018),bioaccumulation experiment was conducted on test organism Cyprinus carpio for 6 weeks for evaluating the bioconcentration factor (BCF value) of test chemical. The study was performed according to other guideline "Bioaccumulation test of a chemical substance in fish or shellfish" provided in "the Notice on the Test Method Concerning New Chemical Substances", respectively under flow through conditions at a temperature of25°C and pH range 6.0-8.5, respectively. Cyprinus carpio (length - 8 dimensionless)was used as a test organism for the study. Test chemical nominal conc. used for the study were 0.5mg/l and 0.05 mg/l, respectively. Range finding study involve the TLm (48 hr) 160 mg/l (w/v) on Rice fish (Oryzias latipes). The bioconcentration factor (BCF value) of test chemical on Cyprinus carpio was determined to be in the range of 0.7-3.5 L/Kg at a conc. of 0.5 mg/l and ≤ 2.6 L/Kg at a conc. of 0.05 mg/l, respectively.

 

In a prediction done using the BCFBAF Program of Estimation Programs Interface was used to predict the bioconcentration factor (BCF) of test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 5.785 L/kg whole body w.w (at 25 deg C).

 

Another predicted data was estimated using Bio-concentration Factor module (ACD (Advanced Chemistry Development)/I-Lab predictive module, 2017)) for predicting the bioconcentration factor (BCF) of test chemical.The bio-concentration Factor of the test chemical was estimated to be 1 dimensionless at pH range 1-14, respectively.

 

On the basis of above results for test chemical, it can be concluded that the BCF value of test chemical was evaluated to beranges from0.7 to 5.785, respectively,which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is not expected to bioaccumulate in the food chain.