Registration Dossier
Registration Dossier
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EC number: 210-557-3 | CAS number: 618-62-2
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- secondary source
- Title:
- IUCLID DATAFILE
- Author:
- unknown
- Year:
- 2 000
- Bibliographic source:
- Esis-Database, European Chemicals Bureau
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 3,5-dichloronitrobenzene
- EC Number:
- 210-557-3
- EC Name:
- 3,5-dichloronitrobenzene
- Cas Number:
- 618-62-2
- Molecular formula:
- C6H3Cl2NO2
- IUPAC Name:
- 1,3-dichloro-5-nitrobenzene
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: aerosol
- Type of inhalation exposure:
- whole body
- Vehicle:
- air
- Details on inhalation exposure:
- Aerosol of a 10% solution in hexan/peanut oil
- Duration of exposure:
- 4 h
- No. of animals per sex per dose:
- 5
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 0.3 mg/L air
- Based on:
- test mat.
- Exp. duration:
- 4 h
Applicant's summary and conclusion
- Interpretation of results:
- other: not acute tox category I
- Remarks:
- Criteria used for interpretation of results: EU
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