Registration Dossier
Registration Dossier
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EC number: 230-426-4 | CAS number: 7128-64-5
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1963
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 963
- Report date:
- 1963
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- yes
- Remarks:
- no data on sex, limited details on animal husbandry, limited details on test compound, observation period not specified, no details on examinations
- GLP compliance:
- no
- Remarks:
- prior to GLP
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- 2,5-thiophenediylbis(5-tert-butyl-1,3-benzoxazole)
- EC Number:
- 230-426-4
- EC Name:
- 2,5-thiophenediylbis(5-tert-butyl-1,3-benzoxazole)
- Cas Number:
- 7128-64-5
- Molecular formula:
- C26H26N2O2S
- IUPAC Name:
- 5-tert-butyl-2-[5-(5-tert-butyl-1,3-benzoxazol-2-yl)thiophen-2-yl]-1,3-benzoxazole
- Details on test material:
- - Physical state: solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: about 120 g
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- not specified
- Doses:
- 1000, 3000, 6000, 10000 mg/kg
- No. of animals per sex per dose:
- 5 animals (sex not specified)
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 10 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: no mortality occurred
- Mortality:
- none
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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