Registration Dossier

Administrative data

Description of key information

Not skin sensitising.

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Assessment on skin sensitising potential, conducted according to LLNA method in mice.

No clinical signs and no mortality were noted. No significant differences between treated and control groups.

The stimulation index SI was found to be below 3 in all treated groups.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

According to the CLP Regulation (EC 1272/2008), skin sensitizer is a substance that will lead to an allergic response following skin contact. In case of a local lymph node assay, a stimulation index of 3 or more is considered as a positive response.

Under the experimental conditions employed, stimulation index was below 3 in all treated groups, thus no classification was applied.