Registration Dossier

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
adsorption / desorption: screening
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter

Description of key information

Key value for chemical safety assessment

Additional information

N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine hydrolyses in contact with water to the corresponding N-[3-(dihydroxymethylsilyl)-2-methylpropyl]ethylenediamine, which have low log Kow values (<3) and thus have low potential for adsorption/desorption. Therefore, in accordance with Column 2 of REACH Annex VIII, the adsorption/desorption screening test does not need to be conducted, and also there is no need for further information on adsorption/desorption.

Though the hydrolysis product is expected to be surface active, the surface activity is weak and non-ionic. Therefore, it is considered appropriate to waive the adsorption testing based on low log Kow, and to get an indicative adsorption potential value based on the log Kow prediction method.

Adsorption of the hydrolysis product N-[3-(dihydroxymethylsilyl)-2-methylpropyl]ethylenediamine

has been estimated using two separate estimation methodologies. The log KOC of 2.8 (Koc of 638.3) (KOCWIN MCI prediction method) and 0.31 (Koc of 2.05) (TGD Kow predicition method) were obtained using an accepted QSAR (SRC EPIWIN v4.10). The result is considered to be reliable.