Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 433-260-2 | CAS number: 168253-59-6
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The substance is characterised by an estimated bioconcentration factor of 128.3 L/kg ww. Both possible hydrolysis products (bis-aspartic-mono-acid triethylester, bis-aspartic-di-acid diethylester) have a calculated BCF value of 3.162 L/kg ww (Currenta, 2011b, 2011c, 2011d).
Key value for chemical safety assessment
- BCF (aquatic species):
- 128.3 L/kg ww
Additional information
As the bioconcentration factor was estimated by the means of EPI-Suite software BCFBAF, the hydrolysis of the substance was not considered and the calculated value solely reflects the bioaccumulation potential of the parent substance.
If the half-life, at environmentally relevant pH values (4-9) and temperature, is greater than 12 hours, it is assumed that the rate of hydrolysis is lower than that for uptake by the exposed organisms (Guidance on information requirements and chemical safety assessment, R.7c, ECHA, 2008c). Therefore, the parent substance as well as the hydrolysis products should be considered for the assessment of the bioaccumulation potential.
Caused by the hydrolysis of the parent substance, bis-aspartic-mono-acid triethylester and bis-aspartic-di-acid diethylester of the parent substance are formed. As the hydrolysis products are more hydrophilic, having an estimated BCF of 3.162 L/kg ww, a low potential for bioaccumulation is assumed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
