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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

ErC50 (72 h) > 118 mg/L and NOErC = 118 mg/L (measured, OECD 201) based on read across from CAS 1066 -42 -8

EC50 (72 h) = 2115 mg/L (QSAR for hydrolysis product methylsilanetriol)


Key value for chemical safety assessment

EC50 for freshwater algae:
2 115 mg/L

Additional information

No data on the toxicity of dimethoxymethylsilane (CAS 16881 -77-9) on algae were available. Due to the rapid hydrolysis of the substance, data from the hydrolysis product, dimethylsilanediol, were considered appropriate to read across.

In a GLP study (2009) according to the OECD guideline 203 the green algae, Pseudokirchneriella subcapitata was exposed to dimethylsilanediol at concentrations of 0 (negative control), 7.5, 15, 30, 60, and 120 mg/L (nominal). The effect value ErC50 (72 h) was found to be >118 mg/L while the 72-h NOErC value is 118 mg/L (both measured).

Furthermore, the calculation with an appropriate QSAR model revealed an EC50 of 2115 mg/L for the hydrolysis product methylsilanetriol.

On this basis, the substance is not considered harmful to algae.