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Short-term toxicity to aquatic invertebrates

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Description of key information

EC50 (48 h) > 117 mg/L (measured, OECD 202) based on read across from CAS 1066 -42 -8

LC50 (48 h) = 29600 mg/L (QSAR for hydrolysis product methylsilanetriol)

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
29 600 mg/L

Additional information

No data on the short term toxicity of dimethoxymethylsilane (CAS 16881 -77-9) to aquatic invertebrates were available. Due to the rapid hydrolysis of the substance, data from the hydrolysis product dimethylsilanediol (CAS 1066 -42 -8), were considered appropriate to read across. The study (2009) was conducted according to the OECD guideline 202 and GLP standards. The test organism, Daphnia magna was exposed under static conditions for 48 h to a nominal concentration of 120 mg test item/L. The 48 -h effect value, EC50 was found to be > 117 mg/L (measured).

 

A QSAR calculation was additionally performed in order to estimate the short term toxicity of the hydrolysis product methylsilanetriol to aquatic invertebrates. The calculation resulted in an LC50 of 29600 mg/L.

 

On this basis the substance is not considered harmful to aquatic invertebrates.