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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

LC50 (96 h) > 126 mg/L (measured, OECD 203) based on read across from CAS 1066 -42 -8

LC50 (96 h) = 100000 mg/L (QSAR for hydrolysis product methylsilanetriol)

Key value for chemical safety assessment

LC50 for freshwater fish:
100 000 mg/L

Additional information

No data on the short term toxicity to fish were available for dimethoxymethylsilane (CAS 16881 -77-9). However due to the rapid hydrolysis of the substance, data from the hydrolysis product dimethylsilanediol (CAS 1066 -42 -8), are considered appropriate to read across.

In the study (2009) conducted under GLP standards and according to the OECD guideline 203, the test organism, Oncorhynchus mykiss was exposed in a limit test and under static conditions for 96 h to a nominal concentration of 120 mg test item/L. The 96-h LC50 value was found to be > 126 mg/L (measured). No mortality or other effects were observed neither in the control nor in the treated test media.

A QSAR calculation was performed to predict the toxicity of the hydrolysis product methylsilanetriol to fish. The calculation resulted in an LC50 of 100000 mg/L for an exposure time of 96 h.

Therefore, it is concluded that the test substance is not harmful to fish.