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EC number: 926-571-4 | CAS number: 1187203-96-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish:
The acute toxicity of the substance to fish (Danio rerio) was tested in a semi-static test. After 96 hours of exposure, a LL50 of >100 mg/L was determined (Neuhahn, 2011a).
The fish were exposed to a range of concentrations, nominally 25, 50 and 100 mg/L of the substance dissolved in dilution water. Defined loadings of the test item led to a certain percentage proportion of dead fish at the end of the 96 hour study period. Mortalities were recorded at 24 hour intervals. Additionally any abnormal behaviour or appearance of the fish was reported every 24 hours.
The results are expressed in terms of Lethal Loading (LL). As the test item is a UVCB substance and no information about the correlation between molecular weight und the structural formula of the test item are available, Water Accommodated Fraction (WAF) were used to test effects at different effective loadings and no specific analysis was performed. With the sponsor's agreement, the content of the test item during the exposure period was verified by DOC determination.
Short-term toxicity to aquatic invertebrates:
The acute toxicity of the substance to aquatic invertebrates (Daphnia magna) was tested in a static test. After 48 hours of exposure, an EL50 of >100 mg/L was determined (Neuhahn, 2011b).
The results are expressed in terms of Effective Loadings (EL). As the test item is a UVCB substance and no information about the correlation between molecular weight and the structural formula of the test item are available, Water Accommodated Fractions (WAF) were used to test effects at different effective loadings and no specific analysis was performed. With the sponsor’s agreement, the content of the test item during the exposure period was verified by DOC determination.
Short-term toxicity to aquatic algae and cyanobacteria:
The toxicity of the substance to aquatic algae (Desmodesmus subspicatus) was tested in a static test. During 72 hours exposure an ErL50 and an ErL10 at >100 mg/L were determined and a NOEC at ≥ 100 mg/L was calculated by a multisampling comparison (according to Williams Multiple Sequential t-Test Procedure) (Neuhahn, 2011c).
The results are expressed in terms of Effective Loadings (EL). As the test item is a UVCB substance and no information about the correlation between molecular weight and the structural formula of the test item are available, Water Accommodated Fractions (WAF) were used to test effects at different effective loadings and no specific analysis was performed. With the sponsor’s agreement, the content of the test item during the exposure period was verified by DOC determination.
Toxicity to microorganisms:
A study was performed to assess the toxicity of the substance to bacteria. The activated sludge from predominantly domestic sewage plant was exposed to the test solution of three nominal concentrations of the substance (10, 100 and 1000 mg/L), blank control solution and solution with positive reference substance for a period of 3 hours. Dissolved oxygen was recorded and respiration rates were calculated. No physico-chemical oxygen consumption was observed at the highest concentration of test substance. The substance showed 6.67 % respiration inhibition of activated sludge at a test item concentration of 1000 mg/L. The EC50 is higher than 1000 mg/L (Neuhahn, 2011d).
Long-term toxicity to fish and long-term toxicity to aquatic invertebrates:
In accordance with section 3 of REACH Annex XI, a study does not need to be conducted as, based on the Exposure Scenarios developed in the Chemical Safety Report, it is demonstrated and documented that throughout the life cycle Strictly Controlled Conditions as set out in Article 18(4)(a) to (f) of REACH do apply.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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