Registration Dossier

Administrative data

Endpoint:
developmental toxicity
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Classification tool software
Title:
Unnamed
Year:
2010

Materials and methods

Principles of method if other than guideline:
The UVCB substance as complex substance is classified by applying the rules for classification of mixtures (EU CLP guidance section 3.7.2 pg 322ff). The classification criteria (as set out in EU CLP Guidance Annex I: 3.7.1 pg 322) can be used to estimate effects derived from that classification/hazard.

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Results (fetuses)

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Any other information on results incl. tables

The calculated classification via mixture rules resulted in "reproductive toxicity: category 1A", triggered by lead compounds with total quantity > 0.3% for worts case.

Applicant's summary and conclusion

Conclusions:
The tool provided a conclusive "Reproductive toxicity Cat1A" of teh UVCB sample, derived on basis of the mixture toxicity rules for a worst case across industry.