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Ecotoxicological information

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Aquatic toxicity studies in fish were performed for the test substance FAT 40045 using methodology similar to OECD TG 203 to evaluate the toxicity potential of the test substance. 96 h LC50 to fish was >1000 mg/L. Whereas aquatic toxicity study in Daphnia magna was performed for a similar substance (which is used here as a read across substance FAT 40336) according to OECD TG 202. 48 h EC50 to daphnids was found to be >100 mg/L. In the key study performed to assess the effect of the test item on the growth of Lemna gibba according to OECD Guideline 221, the nominal EC50-value for yield of dry weight, growth rate of dry weight, yield of frond numbers and growth rate of frond numbers was determined to be >100 mg/L. The nominal EC50-value for yield of dry weight, growth rate of dry weight, yield of frond numbers and growth rate of frond numbers was determined to be >100 mg/L. The overall LOEC was therefore determined to be 0.298 mg/L, the corresponding NOEC could not be observed and is supposed to be below 0.298 mg/L. For microorganisms, studies conducted using sludge from a domestic waste-water treatment plant reported the 3 h IC50 as >400 mg/L. Based on the test data for all the three species (LC50 and EC50: >100 mg/L) FAT 40045 can be classified as 'not toxic' to aquatic organisms.

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