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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
other: read across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Handbook data, limited reporting

Data source

Reference
Reference Type:
review article or handbook
Title:
Toxicology of the eye
Author:
Grant
Year:
1974
Bibliographic source:
2nd Edition. Charles C. Thomas Publishers, Springfield II, USA

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
Similar Substance 03
IUPAC Name:
Similar Substance 03

Results and discussion

In vivo

Results
Remarks on result:
no indication of irritation

Any other information on results incl. tables

No specific information on results more than the reported comment is available

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Criteria used for interpretation of results: EU
Conclusions:
Applied experimentally to rabbit eyes, the substance has been found to be innocuous.