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Short-term toxicity to aquatic invertebrates

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Description of key information

Key data: EC50(48 h) = 43.2 mg/L (nominal); NOEC(48 h) = 25.0 mg/L (nominal); LOEC(48 h) = 50.0 mg/L (nominal).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
43.2 mg/L

Additional information

The short-term toxicity test to aquatic invertebrates (Noack 2012) under semi-static conditions performed according to EU Method C.2., OECD 202 and GLP was rated with RL=1 (reliable without restrictions) and used as a key study. Immobilization to Daphnia magna of the test item was observed at the nominal concentration of 50 mg/L and greater (measured concentrations within 80 - 120% of nominal values).

The EC50 (48 hours) was 43.2 mg/L (95 % confidence limits: 41.3 – 45.1 mg/L), the NOEC after 48 hours was 25.0 mg/L and the LOEC after 48 h was 50.0 mg/L (based on nominal concentrations).

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