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According to REGULATION (EC) No 1907/2006 (ANNEX IX) a bioaccumulation study has not be conducted if the substance has a low potential for bioaccumulation (for instance a log Kow < 3).

Based on its log Kow of -5.45, a low potential for bioaccumulation is expected for tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate. The log Kow of the non-water-based parent acid 2-phosphonobutane-1,2,4-tricarboxylic acid was calculated to be -1.66, also indicating al low potential for bioaccumulation.