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Environmental fate & pathways

Hydrolysis

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Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance is highly insoluble in water
Qualifier:
according to guideline
Guideline:
EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Description of key information

The water solubility was assessed as less than approximately 10 µg/L. As the hydrolysis test is performed at no greater than 50 % of the saturation level, and methodology is required to be able to detect 10 % of the initial concentration, it was considered that achieving an accurate, robust analytical method to detect concentrations in the range of level approximately 0.1 to 0.01 µg/L was not possible. Hence, the study could not be performed.

Key value for chemical safety assessment

Additional information