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Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Pulmonary responses to purified zinc oxide fume
Author:
Kuschner WG, D'Alessandro A, Wintermeyer SF, Wong H, Boushey HA, Blanc PD
Year:
1995
Bibliographic source:
J Investig Med. 1995 Aug;43(4):371-8.
Reference Type:
secondary source
Title:
No information
Author:
European Chemicals Bureau
Year:
2004
Bibliographic source:
EU Risk Assessment Report: CAS 1314-13-2

Materials and methods

Type of study / information:
inhalation exposure to purified zinc oxide fume (Zn particles <100 nm)
Endpoint addressed:
acute toxicity: inhalation

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- primary particael mean diameter: 8-40nM- mass diameter: 170 nm

Method

Details on exposure:
- mean concentration: 16.4 mg/m3 (2.76-37.0 mg/m3)

Results and discussion

Applicant's summary and conclusion