Assess hazard and risk

An important part of the SIEF work with your co-registrants is to compile  information on uses, hazards and risks in order to demonstrate safe use of the substance.

You will need to consider the following regulatory, scientific and technical requirements:


  • Gather information on uses and current conditions of use from the supply chain. Contact your industry association for best practice in your sector;
  • Collect hazard data as requested by REACH information requirements triggered by the tonnage and uses of the substance;
  • Assess the coverage and quality of the hazard information about the substance available within the SIEF;
  • Define the strategy to fill in any resulting data gaps (e.g. carrying out new studies, justifying missing information using scientifically solid read across, data waivers etc.);
  • Agree classification and labelling within the SIEF (based on the hazard data);
  • Record all hazard data and classification in the registration dossier; and
  • If manufacturing or importing more than 10 tonnes per year, you need to carry out the chemical safety assessment (CSA) and record it in a chemical safety report (CSR). Additionally, during the SIEF discussions the co-registrants decide if the lead registrant will submit the chemical safety report jointly on behalf of the co-registrants or if the individual registrants will submit their own CSR separately.