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EC number: 269-130-5 | CAS number: 68187-85-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Remarks:
- Toxicity control of ready biodegradability study according to OECD 301F
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data based on the inhibition control of a ready biodegradability study. This approach is in accordance with the Guidance on information requirements and chemical safety assessment (Chapter R.7b: Endpoint specific guidance, ECHA 2017).
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: Toxicity control from ready biodegradability study according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Hessisches Ministerium für Umwelt, Klimaschutz, Landwirtschaft und Verbraucherschutz, Germany
- Analytical monitoring:
- no
- Details on sampling:
- SAMPLING
- Sampling method: The pressure decrease in the reaction vessels was measured daily. - Vehicle:
- no
- Details on test solutions:
- - Composition of medium: according to guideline OECD 301 F
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- - Source of inoculum/activated sludge: Sewage treatment plant Bensheim, Germany
- Preparation of inoculum for exposure: Activated sludge used for this study was deposited for 15 min and washed by centrifugation. Aliquotes of washed sludge suspension, corresponding to 3.5 g dry material/L were mixed with test water and aerated overnight
- Pretreatment: Sludge was washed by centrifugation, liquid phase was then decanted and solid material was re-suspended in tap water and centrifuged, procedure was repeated 3 times. An aliquot of the final sludge suspension was weighed, dried and ratio of wet sludge to dry weight was determined. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 14 d
- Test temperature:
- 22 °C ± 1 °C
- pH:
- 7.4 - 7.9
- Nominal and measured concentrations:
- Nominal:. 102.87 mg test item/L
- Details on test conditions:
- TEST CONDITIONS
- Composition of medium: according to guideline OECD 301 F
- Suspended solids concentration: 28.7 mg sludge/L per flask
- Continuous darkness: yes
- Other: continuous stirring
TEST SYSTEM
- Culturing apparatus: Manometric Test System with test flasks containing a volume of approx. 500 mL.
- Number of culture flasks/concentration: 1
- Measuring equipment: BSB/BOD-Sensor-System, Aqualytic Dortmund, Germany
- Test performed in closed vessels: yes
- Details of trap for CO2: potassium hydroxide solution (45%)
CONTROL AND BLANK SYSTEM
- Inoculum control: 2 flasks
- Abiotic sterile control: 1 flask (poisoned with CuSO4)
- Other: procedure control: 1 flask
- Reference substance (positive control):
- yes
- Remarks:
- benzoic acid, sodium salt
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 102.87 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks on result:
- other: Result of toxicity control from ready biodegradability test
- Details on results:
- The toxicity control attained 61% biodegradation after 14 d and 62% after 28 d (the test item can be assumed to be not inhibitory to the aerobic activated sludge microorganisms as degradation was >25% within 14 d.)
- Results with reference substance (positive control):
- 94% biodegradation of reference substance after 14 d and 103% after 28 days.
- Validity criteria fulfilled:
- yes
- Remarks:
- For details see cross-referenced study
Reference
Since more than 25% degradation occurred in the toxicity control, the substance is with high probability not toxic to aquatic microorganisms. The test item concentration in the toxicity control of 102.87 mg/L can be used as NOEC value for the toxicity to aquatic microorganisms.
Description of key information
NOEC (14 d) ≥ 102.87 mg/L (nominal, toxicity control, OECD 301F, activated sludge)
Key value for chemical safety assessment
Additional information
Since no studies on the toxicity to aquatic microorganisms are available the results of a ready biodegradability study are used to draw conclusion on the toxicity of the substance to aquatic microorganisms. If a compound biodegrades readily in a biodegradability test or does not inhibit at a certain concentration the degradation of a reference substance in the positive control the substance is not considered toxic to microorganisms and the concentration applied in the toxicity control can be set as the NOEC value. This approach is in accordance with the Guidance on information requirements and chemical safety assessment (Chapter R.7b: Endpoint specific guidance, ECHA 2017).
A substance can be assumed to be not inhibitory to aquatic microorganisms, if in the toxicity control of a ready biodegradation test, more than 25% degradation based on ThOD occurred within 14 days (OECD guideline 301).
For the test item fatty acids, tall-oil, esters with ethylene glycol (CAS 68187-85-9) a biodegradation test according to OECD guideline 301F is available. The test includes a toxicity control, which contains 102.87 mg/L of the test item and 103.69 mg/L benzoic acid. The toxicity control attained 61% degradation after 14 days of incubation. Hence, the substance is considered not toxic to aquatic microorganisms and the test item concentration of 102.87 mg/L can be used as NOEC.
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