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Diss Factsheets
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A reaction mixture containing the following components;A. Tetralithium [2(or 3), 9 (or 10), 16 (or 17), 23 (or 24)-tetrakis (3-sulfonato-propylsulfonyl) phthalocyaninato]cupurate (II)B. Trilithium [3-(2-hydroxylpropylsulfamoyl)propylsulfonyl]tris (3-sulfonato-propylsulfonyl)phthalocyaninatocupurate (II)C.Dilithium bis [3-(2-hydroxylpropylsulfamoyl)propylsulfonyl] bis (3-sulfonato-propylsulfonyl)phthalocyaninatocupurate (II)D. Lithium tris [3-(2-hydroxylpropylsulfamoyl)propylsulfonyl] (3-sulfonato-propylsulfonyl)phthalocyaninatocupurate (II)E. Tetrakis [3-(2-hydroxpropylsulfamoyl) proppylsulfonyl]phthalocyaninatocupurate (II)In the ratio A:B:C:D:E 6.25 : 25 : 37.5 : 25 : 6.25
EC number: 472-040-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Toxicity to aquatic plants other than algae
Some information in this page has been claimed confidential.
Administrative data
- Endpoint:
- toxicity to aquatic plants other than algae
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- The range-finding test was conducted between 16 March and 23 March 2005.The definitive test between 27 April and 4 May 2005. The positive control (Safepharm Laboratories Project Number: 39/743) was conducted between 31 January 2005 and 7 February 2005.
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 221 (Lemna sp. Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Test substance concentration measured on days 0, 2, 5 and 7
Test solutions
- Vehicle:
- no
- Details on test solutions:
- Culture medium control and test substance nominal concentrations of 1.0, 3.2, 10, 32, 100 and 320 mg/l
Test organisms
- Test organisms (species):
- Lemna minor
- Details on test organisms:
- Test organisms from internal laboratory cultures
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 7 d
Test conditions
- Hardness:
- Not Applicable
- Test temperature:
- 24 °C (+/- 1 °C)
- pH:
- pH at the start of the test (time 0) was 6.7 in all test vessels and at 7 days pH ranged from 7.0 to 7.4. A general increase in pH betwen media renewal periods was observed. This effect was considered to be due to bicarbonate in the culture medium being used as a source of CO2 for respiration, which results in an increase in pH of the culture medium.
- Dissolved oxygen:
- Not Applicable
- Salinity:
- Not Applicable
- Nominal and measured concentrations:
- Test concentrations were a culture medium control and test substance at nominal concentrations of 1.0, 3.2, 10, 32, 100 and 320 mg/l. The measured test concentrations ranged from 85% to 107% of nominal with the expection of the 1.0 and 3.2 mg/l test concentrations of 71% and 76% of nominal repectively.
- Details on test conditions:
- The test vessels were glass conical flasks. Three flasks each containing 250ml of medium were prepared for the control and each treatment group. The control group was maintained under identical conditions to the treatment groups but not exposed to test material. Each control and test flask was inoculated with 3 colonies of Lemna minor (total 9 fronds). The flasks were then incubated at 24 degrees centrigrade +/- 1 degree centrigrade under constant illumination for 7 days (intensity approximately 7000 lux).
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorophenol (run every six months)
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 7 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Average specific growth rate (Frond number)
- Key result
- Duration:
- 7 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 320 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Average specific growth rate (Frond number)
- Details on results:
- Results were as follows:Average specific growth rate (frond number) > 320* mg/l, NOEC 1 mg/lAverage specific growth rate (dry weight) = 280 mg/l, NOEC 3.2 mg/lYield (frond number) = 210 mg/l, NOEC 1.0 mg/lYield (dry weight) = 19 mg/l, NOEC 3.2 mg/l* It was not possible to calculate an ERC50 value for the average specific growth rate rata based on frond numbers as no concentration tested resulted in greater than 50% inhibition.Assessment of toxicity is based on average specific growth rate as this is considered to be the endpoint which is most accurate for the assessment of inhibition and/or toxcity.
- Results with reference substance (positive control):
- Results for the positive control (3,5-dichlorophenol) were as follows:Average specific growth rate (frond number) > 3.2 mg/l, NOEC 1.25 mg/lAverage specific growth rate (dry weight) = 2.6 mg/l, NOEC 2.5 mg/lYield (frond number) = 2.0 mg/l, NOEC 0.625 mg/lYield (dry weight) = 2.4 mg/l, NOEC 1.25 mg/lThe positive control is run every six months in the laboratory to confirm that the test system is workign as expected.
- Reported statistics and error estimates:
- One way analysis of variance incorporating Bartlett's test for homogeneity of variance (Sokal and Rohlf 1981) and Dunnett's multiple comparison procedure for comparing several treatments with a control (Dunnett 1955) was carried out on the average specific growth rate data and the yield data at 7 days for the control and all test concentrations to determine any statistical ly signifincant differences betwen the test and control groups. All statistical analyses were performed using the SAS computer software package (SAS 1999- 2001)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test substance average specific growth rate EC50 for frond numbers and dry weight were both > 100 mg/l. By analogy to the result on FJC-003E, the Test substance is considered to be non toxic to duckweed (Lemna minor) based on average specific growth rate.
- Executive summary:
Introduction.
A study was performed to assess the effect of the test material on the growth of the freshwater plant Lemna minor. The method followed that described in the draft OECD Guideline "Lemna Growth Inhibition Test (April 2004)".
Methods.
Following a preliminary range-finding test, Lemna minor was exposed to an aqueous solution of FJC-003E at a concentration of 100 mg active ingredient (ai) /l (six replicate flasks) for a period of 7 days, under constant illumination at a temperature of 24 ± 2°C. The test solutions were renewed on days 3 and 5. The number of fronds in each control and treatment group was recorded on days 0, 3, 5 and 7 along with observations on plant development.
Results and Conclusion.
The average specific growth rate EC50 for frond number and dry weight was >100 mg/l. The Yield EC50 for frond number and dry weight was >100 mg/l. By analogy to the result on FJC-003E, the test substance is considered to be non-toxic to duckweed (Lemna minor) based on average specific growth rate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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