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Registration Dossier
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Diss Factsheets
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EC number: 700-502-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2008-10-16 to 2008-10-18
- Reliability:
- 1 (reliable without restriction)
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- Principles of method if other than guideline:
- not applicable
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- other: soil/sewage sludge (Estimation using HPLC)
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- not applicable
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
not applicable - Radiolabelling:
- no
Study design
- Test temperature:
- 25 °C
HPLC method
- Details on study design: HPLC method:
- HPLC system: Merck-Hitachi LaChrom HPLC system
Analytical column: LiChrospher 100 CN (5μm) 250x4 No.: 638212
Detector: UV at 254 nm and 530 nm Mobil Phase: Methanol : Water : Trifluoroacetic acid = = 60 : 40 : 0.04 Flow: 0.8 ml/min.
Injection volume: 10 µl
Temperature: 25 °C
Mobil Phase: Methanol : Water : Trifluoroacetic acid mixture with the ratio 60 : 40 : 0.04 (v/v)
Solution of the Test Item: 1.0 mg/ml F 213 Red in Methanol
Results and discussion
Adsorption coefficientopen allclose all
- Type:
- Koc
- Value:
- ca. 0.645
- Type:
- log Koc
- Value:
- > 5
Results: HPLC method
- Details on results (HPLC method):
- The adsorption coefficient Koc was determined based on a calibration curve using 8 reference items. In order to confirm the result obtained in this study for the log Koc value of DDT an additional measurement was performed subsequent to this study at a higher concentration rate. The capacity factors k’ were calculated from the dead time and retention times of the reference substances. The log k’ data of the reference substances were plotted against their log Koc values. F 213 Red eluted after all reference substances.
Any other information on results incl. tables
no remarks
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- In the course of the adsorption/desorption study the adsorption coefficient (Koc) of F 213 Red was estimated, using high performance liquid chromatography. The test item eluted later than the reference substance with highest Koc (DDT). Therefore, the Koc of the test item is above the calibrated range. In conclusion, the estimated log Koc: > 5.0. The quality criteria were met, as values of log Koc derived from individual measurements fell within a range of 0.25 log units and the correlation coefficient R was >0.95.
- Executive summary:
The log Koc was estimated at > 5.0.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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