Registration Dossier
Registration Dossier
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EC number: 206-743-9 | CAS number: 372-09-8
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- grey literature
- Title:
- No information
- Year:
- 2 006
- Bibliographic source:
- SIDS INITIAL ASSESSMENT PROFILE Cyanoacetates - SIAM 23, 17-20 October 2006
Materials and methods
- Principles of method if other than guideline:
- Method not known
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Cyanoacetic acid
- EC Number:
- 206-743-9
- EC Name:
- Cyanoacetic acid
- Cas Number:
- 372-09-8
- Molecular formula:
- C3H3NO2
- IUPAC Name:
- cyanoacetic acid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: aerosol
- Type of inhalation exposure:
- not specified
- Duration of exposure:
- 4 h
- Concentrations:
- 50% in water
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 1 900 mg/m³ air
- Exp. duration:
- 4 h
- Clinical signs:
- other: The most prominent symptoms were signs of severe irritation of eyes, mouth and respiratory tract
Applicant's summary and conclusion
- Interpretation of results:
- harmful
- Remarks:
- Migrated information Criteria used for interpretation of results: not specified
- Conclusions:
- The substance may be harmful if inhaled.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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