Registration Dossier
Registration Dossier
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EC number: 414-240-2 | CAS number: 6914-71-2
Genetic toxicity: in vivo
Administrative data
- Endpoint:
- in vivo mammalian germ cell study: cytogenicity / chromosome aberration
- Remarks:
- Type of genotoxicity: chromosome aberration
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 474 / micronucleus test
- GLP compliance:
- yes
- Type of assay:
- other: Non-bacteriological test in vivo - 6th amendment data
Test animals
- Species:
- other: mus/ HSD/ Win: NMRI
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- maize germ oil
- No. of animals per sex per dose:
- Female: 2000 mg/kg; No. of animals: ; Sacrifice times: hours
Results and discussion
Test results
- Toxicity:
- yes
- Remarks:
- Doses producing toxicity: No clinical symptomes at 2000 mg/kg
- Additional information on results:
- Observations:
No toxicological or cytotoxical symptoms (PCE/ NCE in the
bone marrow) were induced. There were no signs of a
mutagenic potential.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): negative
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