Registration Dossier
Registration Dossier
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EC number: 815-137-9 | CAS number: 573762-62-6
Flammability
Administrative data
- Endpoint:
- flammable solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 31 AUG 2022 to 05 OCT 2022
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 022
- Report date:
- 2022
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)
- Version / remarks:
- 2019
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 5-amino-3-(trifluoromethyl)pyridine-2-carbonitrile
- EC Number:
- 815-137-9
- Cas Number:
- 573762-62-6
- Molecular formula:
- C7H4F3N3
- IUPAC Name:
- 5-amino-3-(trifluoromethyl)pyridine-2-carbonitrile
- Details on test material:
- - Appearence : Slightly yellowish brown fine powder
- CAS Number: 573762-62-6
- Molecular formula: C7H4F3N3
- Molecular weight: 187.12
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- lot/batch number of test material: 22CN32583
- Expiry date: 30 March 2024 (retest date)
- Physical Description: Almost white to yellow powder (determined by Charles River Den Bosch)
- Purity: 100.6%
- Purity correction factor: not required
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: At room temperature
- Stability under storage conditions: not indicated
- Stability under test conditions: not indicated
- Solubility and stability of the test item in the solvent/vehicle: not relevant
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing (e.g. warming, grinding): no treatment
Results and discussion
Flammable solids
- Key result
- Test procedure:
- burning rate test: preliminary screening test
- Burning time:
- 1 s
Any other information on results incl. tables
The flame of the gas burner did ignite the test material pile. The test material melted, burned with an orange flame, and turned into a black residue. Thick grey smoke was observed. After removal of the ignition source, the flame extinguished after 1 second and no propagation of combustion was observed.
Applicant's summary and conclusion
- Interpretation of results:
- not classified based on GHS criteria
- Conclusions:
- The preliminary screening test was performed for the determination of the flammability of JNJ-61232574-AAA (T003630).
No propagation of combustion of the test material along 200 mm length of the pile within 2 minutes was observed. According to the guidelines, performance of the burning rate test is not required. Based on the results obtained, the test material is considered ‘not flammable’.
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