Registration Dossier
Registration Dossier
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EC number: 279-251-5 | CAS number: 79752-03-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- Documentation about the justification is provided in attachment (See Supporting information). The reliability assessment of the prediction is presented in the attached document as well (QPRF). QSAR model reporting format is presented in the QMRF file attached.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
- Principles of method if other than guideline:
- Lombardo A, Pizzo F, Benfenati E, Manganaro A, Ferrari T, Gini G (2014). A new in silico classification model for ready biodegradability, based on molecular fragments. Chemosphere. 108, 10–16 http://dx.doi.org/10.1016/j.chemosphere.2014.02.073
- Specific details on test material used for the study:
- CC(=O)N1C2=CC=CC=C2CCC3=C1C=C(C=C3)[N+](=O)[O-]
- Interpretation of results:
- not readily biodegradable
Reference
The prediction was deemed to be non reliable on the basis of the parameters listed above. The molecule does not fall into the applicability domain of the model.
Description of key information
The QSAR prediction cannot be considered fully reliable. However, there are some groups that hints the substance is not readily biodegradable. Overall, ready biodegradability can be excluded for the substance.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
Additional information
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