Registration Dossier
Registration Dossier
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EC number: 820-064-0 | CAS number: 13095-67-5
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 1 000 g/L
- Conc. based on:
- test mat.
- Remarks on result:
- other: test performed at room temperature. No exact value available.
- Details on results:
- The method used yielded reliable results, based on chromatograms with UV detection.
A one day old and a freshly prepared saturated solution were prepared for quantitation to control and to confirm the results of the three day experiment according to OECD Method 105.
The experiment according to the OECD method showed less than 3% difference in the concentrations on three consecutive days (acceptance criteria 15 %).
The control experiment yielded a difference of only 6%.
The solubility of Dipotassium malonate in water was established as 1.00 g/mL on the 3rd day of the experiment. - Conclusions:
- The water solubility of dipotassium malonate was determined to be 1.00 g/mL (= 1000 g/L)
- Executive summary:
The water solubility of dipotassium malonate was assessed by the shake flask method in line with OECD guideline 105.
The test concentration in a saturated solution as determined by means of HPLC was found to be 1.00 g/mL.
Reference
Sample ID |
Nominal Concentration g/mL |
Calculated Concentration μg/mL |
Dilution Factor Test-Site |
Mean Final Conc. g/mL* |
Mean g/mL* |
3rdday |
1.00 |
105.5 |
10000 |
0.987 |
|
3rdday |
1.00 |
95.15 |
10000 |
1.00 |
|
2ndday |
1.00 |
100.7 |
10000 |
||
2ndday |
1.00 |
95.81 |
10000 |
0.982 |
|
1stday |
1.00 |
98.03 |
10000 |
||
1stday |
1.00 |
96.78 |
10000 |
0.974 |
|
Control 24 h |
1.10 |
103.5 |
10000 |
1.06 |
|
Control 24 h |
1.10 |
102.8 |
10000 |
1.03 |
|
Control 0 h |
1.10 |
112.6 |
10000 |
||
Control 0 h |
1.10 |
104.9 |
10000 |
1.09 |
Description of key information
Key value for chemical safety assessment
- Water solubility:
- 1 000 g/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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