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Diss Factsheets
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EC number: 610-979-1 | CAS number: 53207-58-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- From December 5, 1991 to January 13, 1992
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study design appears to follow EU method C.2 with deviations.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Deviations:
- yes
- Remarks:
- No evidence that test concentrations were maintained during exposure.
- GLP compliance:
- no
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- - Name of test material (as cited in study report): TK 13110 (Generic/Trade name: CG 21-1201)
- Batch No.: 1197
- Expiration date of the lot/batch: 09/93
- Storage condition of test material: room temperature
- Purity: 98.3%
- Physical state: white solid
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- Stock solutions:
3 g test substance were mixed with 18 g from an aqueous solution containing 0.4% Arkopal (alkylphenol-polyglycol-ether) by means of a marble-mill during about 24 hours. 1 mL from this mixture was mixed with and made up to 100 mL with water making dilution 1:100.
Test concentrations:
- Nominal: 1,8, 3.2, 5.8, 10 and 18 mg test substance/L.
- Controls: Blank: water
Vehicle: 0.643 mg Arkopal/L.
Calculated amounts of the dilution 1:100 to produce the desired test concentrations were given into the water and were homogeneously distributed.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- - Common name: Daphnia magna
- Strain: Straus 1820
- Source: CIBA-GEIGY Ltd., testing facility
- Feeding during test: none
- Age at study initiation (mean and range, SD): 6-24 h at the start of the test
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 240 mg CaCO3/l
- Test temperature:
- 20+/-1°C
- pH:
- 7.7 - 7.8
- Dissolved oxygen:
- 98 - 100%
- Salinity:
- Freshwater
- Nominal and measured concentrations:
- 1.8, 3.2, 5.8, 10, 18 mg/l (nominal)
- Details on test conditions:
- TEST SYSTEM
- Test vessel: beakers covered with watch glasses (100 mL solution per beaker)
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
- No. of vessels per vehicle control (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: reconstituted water
- Intervals of water quality measurement: 0 and 48 hours
- Reconstituted water containing: 65 mg NaHCO3, 294 mg CaCl2.2H2O, 123 mg MgSO4.7H2O, 6 mg KCl in 1000 mL bidistilled water.
The water was aerated with clean air for at least 24 hours before use.
OTHER TEST CONDITIONS
- Photoperiod: 16 hours fluorescent light daily
- Light intensity: approximately 1500 lux - Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Observed values
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Remarks:
- calculated
- Effect conc.:
- 14 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% confidence limit: 12 - 16 mg/l
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 18 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Observed values
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 18 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- - Immobilization in controls: no immoblization in blank and vehicle controls
- Results with reference substance (positive control):
- No reference substance control
- Reported statistics and error estimates:
- The EC50 values were calculated according to BERKSON, JASA 48 (1953), 569-599.
EC values were graphically determined on gausso-logarithmic probability paper.
Any other information on results incl. tables
Values are based only on nominal concentrations.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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