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EC number: 202-869-3 | CAS number: 100-60-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48-h EC50 value in aquatic invertebrates is >100 mg/L (nominal).
Key value for chemical safety assessment
Additional information
The acute toxicity to aquatic invertebrates was determined in a study according to DIN 38 412, part 11 (BASF, 1989). In this study daphnids (D. magna, 4 replicates of 5 animals per concentration) were exposed to nominal test concentrations of 0 (control), 10, 18, 32, 58 and 100 mg/L for 48 hours under static conditions. Test concentrations were not analytical verified. Immobility of daphnids was recorded after 3, 6, 24 and 48 hours exposure. In the study a significant increase in pH was noted directly after addition of test substance to the medium. This rise in pH was most pronounced at the higher test concentrations. Therefore, an additional 100 mg/L concentration was tested in which the pH was adjusted. In the test groups not neutralised for pH an effect on mobility was first noted at 32 mg/L with 5% immobility after 48 hours exposure. At this concentration an 'initial stun' of 20% immobility was noted at 3 hours exposure. Both in the 58 mg/L and 100 mg/L test groups full immobilisation of daphnids was observed. Based on these findings the 48 -h EC50 value was determined at 45 mg/L. In the 100 mg/L test concentration which was adjusted for pH however, only 45% immobility was recorded after 48 hours.
Based on these findings, it may be concluded that the effects observed are partly attributable to the increased pH rather than to the test substance exposure alone. In the environment, the effect of the rapidly increasing pH on aquatic organisms depends on the buffer capacity of the aquatic ecosystem. There is a possibility that the emission of the substance could locally increase the pH in the aquatic environment. However, normally the pH of effluents is measured frequently to maintain water quality and the range of pH can be managed properly to prevent adverse effects on the aquatic environment. Therefore, a significant increase of the pH of the receiving water is not expected. Generally the changes in pH of the receiving water should stay within the natural range of the pH, and for this reason, adverse effects on the aquatic environment are not expected.
Nonetheless, as effects on daphnids was still visble after neutralisation of pH, for environmental assessment an 48 -h EC50 value of 45 mg/L is taken as a worst case approach.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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