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EC number: 270-109-8 | CAS number: 68411-20-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
In a test according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test) a degradation of 24% after 28 days was observed. In conclusion Butanal, reaction products with aniline is not readily biodegradable.
Two tests in accordance with the EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test) two tests were conducted with different variations. In the first study two test concentrations (0.5/2 mg/L) were tested. In the other study, a test concentration of 2 mg / L was examined by using a solubilizer. During the latter test the test substance was continuously stirred. However, the maximum degradation rate in these tests was 37%. For this reason, Butanal, reaction products with aniline must be classified as “Not readily biodegradable”.
A further test according to OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II)) showed 39% degradataion after 56 days.
According to section 1 of REACH annex XI, the performance of a study for Biodegradation in a water-sediment system an for biodegradation in soil are scientifically unjustified. In biodegradation test in water, biodegradation of 24 to 39% was noticed. This percentage reflects to the part of the substance hydrolysing rapidly to aniline. The remaining about 70% were found stable under test conditions. The final hydrolysis product 3-ethyl-4-propyl-quinoline is probably not biodegradable. Just the closed-bottle tests performed with low concentrations of the test substance are considered similar to higher tier tests as e.g. a simulation test in surface water. It is therefore expected that such a test would not result in significant increase in knowledge, and the P criterion for the water compartment is considered to be fulfilled.
Considering the behaviour of the substance in soil and sediment, two processes are expected:
1. Hydrolysis of the hydrolysable portion (about 30%) of the substance with subsequent biodegradation of aniline.
2. Adsorption of the substance to solid particles. The adsorption coefficient of the substance is in a broad range of logKoc 2.8 -6.5 with a weighted average of logKoc= 4.9. The stable part of the substance is adsorbed to particles due to the strong adsorption potential. Strongly adsorbed substances, either physically or chemically bound, are usually not available to biodegradation.
It is therefore expected that simulation testing would not result in sufficient increase in knowledge in order to re-assess the P criterion.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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