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EC number: 229-929-1 | CAS number: 6843-66-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72 h) = 9 mg/L and NOEC = 1.1 mg/L (meas. arithm. mean, OECD 201) based on read across to the hydrolysis product CAS 947-42-2
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 9 mg/L
- EC10 or NOEC for freshwater algae:
- 1.1 mg/L
Additional information
No data concerning toxicity to algae are available for the target substance Dimethoxydiphenylsilane (CAS 6843 -66 -9). Due to the rapid rate of hydrolysis of the substance (0.6 h at 20 -25°C and pH 7), it was considered appropriate to use measured data of its hydrolysis product Diphenylsilanediol (CAS 947-42-2) to determine the toxicity of the substance to algae.
A study (2004) is available testing the toxicity of Diphenylsilanediol (CAS 947-42-2), which is the hydrolysis product of the target substance, to algae. The test was conducted according to OECD 201 guidance and GLP standards. Pseudokirchneriella subcapitata as the test organism was exposed for 72 h to the nominal test item concentrations of 0 (control), 0.47, 0.94, 1.9, 3.8, 7.5 and 15 mg/L (mean measured: 0, 0.55, 1.1, 2.2, 4.4, 9.0 and 18 mg/L). The test item concentrations in the medium were analytically monitored via HPLC method. The recoveries were > 80% of the nominal values. Biological effects by the substance on algae were observed resulting in an ErC50 (72 h) of 9 mg/L and a NOErC (72 h) of 1.1 mg/L (both mean measured). This study is considered reliable and was selected as key.
Additional supporting information was withdrawn from a study on the toxicity of the related substance Cyclohexyldimethoxymethylsilane (CAS 17865-32-6) to algae. The test was conducted according to the OECD guidance 201 and GLP standards. Desmodesmus subspicatus was exposed for 72 h to the nominal test item concentrations of 0 (control), 6.25, 12.5, 25, 50 and 100 mg/L. The study resulted in an ErC50 (72 h) of 35 mg/L and a NOErC (72 h) of 12.5 mg/L (both nominal).
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