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Diss Factsheets
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EC number: 916-226-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
As the substance consists of four components, the logPow values range between -0.92 and 4.73. The logPow of the main component accounts for 2.22 (Quaternary propoxylated fatty amine)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.22
Additional information
Octanol-water partition coefficients are commonly determined applying the HPLC or the shake-flask method. Both methods are not applicable for the substance as:
- the substance contains components which cannot be detected via common detectors hampering the determination of the partition coefficient by the means of the HPLC-method
- the substance as a whole has surface active properties hampering the reliable determination of the partition coefficient by the means of the shake-flask method as well as the HPLC-method
Therefore, the partition behaviour of the substance was preferably described by the logPow values of the individual components accounting for:
-0.92 (propane-1,2 -diole)
2.22 (Benzenemethanaminium, N-dodecyl-N,N-bis(2-hydroxypropyl)-, chloride (“Quaternary propoxylated fatty amine”))
2.3 (benzyl chloride)
4.73 (1,1'-(dodecylimino)dipropan-2-ol (“Propoxylated fatty amine”))
In the absence of measured data, the octanol-water partition coefficients for the "Quaternary propoxylated fatty amine” and "Propoxylated fatty amine" were predicted using the Estimation Program Interface EPI-Suite version 4.1. The applied estimation modell is assumed to be applicable as the molecular weight as well as structural fragments of the two substances are within the modell domain.
LogPow values for propane-1,2 -diole and bezyl chloride were experimentally determined and reported in peer-reviewed hand books or data collections, respectively. Despite no further information is available on the methodology follwed, these studies were scored as reliable and used for the assessement as the data is obtained from a collection of peer-reviewed data quoted as reliable according to the Guidance Document R.7a (ECHA, 2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.