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EC number: 205-293-0 | CAS number: 137-42-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Data is from IUCLID dataset
- Qualifier:
- according to guideline
- Guideline:
- other: as mention below
- Principles of method if other than guideline:
- Pseudomonas cell proliferation inhibition test by the chemical metam-sodium for 18 hrs was carried out.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material : Metam-sodium
- Molecular formula : C2H4NNaS2
- Molecular weight : 129.1826 g/mol
- Smiles notation : C(=S)(NC)[S-].[Na+]
- InChl : 1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1
- Substance type: Organic
- Physical state: Solid
- Chemical source: UCB–Chemicals Gent - Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Pseudomonas putida
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 18 h
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 18 h
- Dose descriptor:
- EC10
- Effect conc.:
- 0.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: cell proliferation inhibition
- Remarks on result:
- other: Other details not known
- Validity criteria fulfilled:
- not specified
- Conclusions:
- After the 18 hrs exposure of chemical with the test organism, the EC10 was observed at 0.6 mg/l.
- Executive summary:
Pseudomonas cell proliferation inhibition test by the chemical metam-sodium for 18 hrs was carried out. After the 18 hrs exposure of chemical with the test organism, the EC10 was observed at 0.6 mg/l. Thus chemical was consider as toxic to the growth of microorganism Pseudomonas putida.
Reference
Description of key information
Pseudomonas cell proliferation inhibition test by the chemical metam-sodium for 18 hrs was carried out. After the 18 hrs exposure of chemical with the test organism, the EC10 was observed at 0.6 mg/l. Thus chemical was consider as toxic to the growth of microorganism Pseudomonas putida.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 0.6 mg/L
Additional information
Based on the various experimental data for the target chemical Metam-sodium (137-42-8) study have been reviewed to determine toxic nature of on the growth and other activity of invertebrates. The studies are as mentioned below:
In the first study for the target chemical Metam-sodium (137-42-8) from (IUCLID dataset 2000) toxicity was measure on the growth of microorganisms. Pseudomonas cell proliferation inhibition test by the chemical metam-sodium for 18 hrs was carried out. After the 18 hrs exposure of chemical with the test organism, the EC10 was observed at 0.6 mg/l. Thus chemical was consider as toxic to the growth of microorganism Pseudomonas putida.
Similarly in the second study for the target chemical Metam-sodium (137-42-8) from (IUCLID dataset 2000) determine the nature of chemical on the microorganisms. Aim of this study was to determine the toxic effect of chemical on the Short-term breathing of activated sludge (aquatic bacteria). After the exposure of chemical metam-sodium with the test organism activated sludge, the EC20 was observed at > 1995 mg/l. Thus chemical was consider as nontoxic to the growth of microorganism Pseudomonas putida.
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