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Diss Factsheets
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EC number: 203-039-3 | CAS number: 102-54-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- study only continued for 24 hours
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 24 h
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 2.5 mg/L
- Nominal / measured:
- nominal
- Remarks on result:
- other: Technical product, undiluted
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 4 mg/L
- Nominal / measured:
- nominal
- Remarks on result:
- other: Technical product, diluted in Acetone
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 1.5 mg/L
- Nominal / measured:
- nominal
- Remarks on result:
- other: Sublimed and uncrystallised products, diluted in acetone
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 0.2 mg/L
- Nominal / measured:
- nominal
- Remarks on result:
- other: technical, diluted in acetone
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 0.5 mg/L
- Nominal / measured:
- nominal
- Remarks on result:
- other: sublimed and uncrystalised products, diluted in acetone
- Validity criteria fulfilled:
- yes
- Conclusions:
- 3 forms of ferrocene were tested in a study performed that was similar to OECD Guideline 202. Between the 3 different forms, EC50 values showed no hugely significant differences. Technical grade product diluted in Acetone gave EC50 24hr = 4 mg/l, sublimed and uncrystallised products both diluted in acetone gave EC50 24hr = 1.5 mg/l. They show however, that in acute tests daphnia magna are somewhat more sensitive to ferrocene than fish. For a CSA value as this study was only performed for 24 hours, the EC50 values have been decreased by 50% to allow for 48 hour exposure. Therefore technical grade product diluted in Acetone has an EC50 48hr = 2 mg/l with sublimed and uncrystallised products both diluted in acetone, having EC50 48 hr = 0.75 mg/l. Value used in CSA is EC50 (48hr) = 1.17 mg/l
Reference
Description of key information
In a study performed to guidelines similar to OECD 202, 3 forms of ferrocene were tested.
Technical grade product diluted in Acetone has an EC50 (48 hr) = 2 mg/l and the sublimed and uncrystallised products both diluted in acetone have EC50 (48 hr) = 0.75 mg/l.
Average EC50 for the 3 forms used in CSA is EC50 (48hr) = 1.17 mg/l
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 1.17 mg/L
Additional information
3 forms of ferrocene were tested in a study performed that was similar to OECD Guideline 202. Between the 3 different forms, EC50 values showed no hugely significant differences. Technical grade product diluted in Acetone gave EC50 24hr = 4 mg/l, sublimed and uncrystallised products both diluted in acetone gave EC50 24hr = 1.5 mg/l. They show however, that in acute tests daphnia magna are somewhat more sensitive to ferrocene than fish. As this study was only performed for 24 hours for a CSA value , the EC50 values have been decreased by 50% to allow for 48 hour exposure. Therefore technical grade product diluted in Acetone has an EC50 48hr = 2 mg/l with sublimed and uncrystallised products both diluted in acetone, having EC50 48 hr = 0.75mg/l.
Value used in CSA is EC50 (48hr) = 1.17 mg/l
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