Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Referred in a recognized source of peer reviewed scientific data on chemicals

Data source

Reference
Reference Type:
review article or handbook
Title:
Toxicological Profile for Total Petroleum Hydrocarbons (TPH)
Author:
ATSDR
Year:
1999
Bibliographic source:
ATSDR September 1999.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Acute Dermal exposure
Principles of method if other than guideline:
Acute Dermal exposure
GLP compliance:
not specified
Test type:
other: Acute Dermal exposure

Test material

Constituent 1
Reference substance name:
Paraffin oils/waxes
IUPAC Name:
Paraffin oils/waxes
Details on test material:
Paraffin oils/waxes

Results and discussion

Any other information on results incl. tables

Study results:

 

No mortality or clinical signs of toxicity were observed

 

LD0 (rabbit, dermal) = 2000 mg/kg bw;

LD50 (rabbit, dermal) > 2000 mg/kg bw

Applicant's summary and conclusion

Conclusions:
LD0 (rabbit, dermal) = 2000 mg/kg bw;
LD50 (rabbit, dermal) > 2000 mg/kg bw