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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The acute toxicity of 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione to fish (Danio rerio) was tested according to "Letale Wirkung beim Zebrabärbling -Brachydanio rerio-" (LC0 , LC50 , LC100; 48-96 Stunden) Verfahrensvorschlag: Umweltbundesamt Berlin, Stand Mai 1984. During 96 hours exposure the LC0 was measured at 22 mg/L and LC100 at 63 mg/L; and goemetric mean LC0/LC100 was calculated at 37.2 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
37.2 mg/L

Additional information

At defined concentrations of the substance arise after the testing period each percentages of dead fish. The LC0 and LC100 values ​​from this test will be determined directly, while the LC50-value calculation or graphically is determined from the dose-response curve.

Brachydanio rerio was exposed under static condition for 96 h to seven concentrations (7.8, 11, 16, 22, 31, 44 and 63 mg/L) of the test substance. The determination showed a LC0 at 22 mg/L and a LC100 at 63.0 mg/L, and the geometric mean LC0/LC100 was calculated at 37.2 mg/L