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EC number: 915-730-3
CAS number: -
The dermal acute toxicity of the
substance, a yellow liquid, was examined according to a similar to OECD
TG 402, 1987, protocol. First a preliminary study was performed with x
males and females. In the final study eight male and eight female albino
rats (Sprague-Dawley CD strain) were used. The animals weighing between
180 and 280 grams, were clipped on the day prior to dosing and the test
substance, prepared in the diluent supplied, was applied onto the skin
at 5000 mg/kg bw. The volume of the
solution administered was 0.5 ml/100 g bw.
In the preliminary study no mortality
occurred in 72h. In the main study none of the test animals showed any
clinical signs indicative of systemic toxicity. All of the animals
remained healthy throughout the study and gained weight in a normal
manner. At necropsy performed on the survivors at term, none of the
animals had any signs indicative of systemic toxicity. The dermal LD50
was greater than 5000 mg/kg bw.
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