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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Endpoint:
toxicity to microorganisms, other
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Meets national standard method with acceptable restrictions, well documented

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Unnamed
Year:
1977
Reference Type:
publication
Title:
Unnamed
Year:
1980
Report date:
1980

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: DIN 38412, part 8 (German Standard Method)
Principles of method if other than guideline:
Cell proliferation inhibition test, measurement of the turbidity at 436 nm.
GLP compliance:
no

Test material

1
Chemical structure
Reference substance name:
Butyraldehyde
EC Number:
204-646-6
EC Name:
Butyraldehyde
Cas Number:
123-72-8
Molecular formula:
C4H8O
IUPAC Name:
butanal
Test material form:
liquid: volatile
Details on test material:
No data
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
Not applicable

Sampling and analysis

Analytical monitoring:
no
Details on sampling:
Not applicable

Test solutions

Vehicle:
no
Details on test solutions:
No data

Test organisms

Test organisms (species):
Pseudomonas putida
Details on inoculum:
Laboratory culture

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
16 h
Post exposure observation period:
Not applicable

Test conditions

Hardness:
No data
Test temperature:
25ºC
pH:
No data
Dissolved oxygen:
No data
Salinity:
Not applicable
Nominal and measured concentrations:
Nominal concentrations not reported.
Details on test conditions:
No data
Reference substance (positive control):
not specified

Results and discussion

Effect concentrations
Duration:
16 h
Dose descriptor:
other: Toxic Threshold Concentration, MIC
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Details on results:
Cell proliferation inhibition: the toxic threshold concentration (=TGK) is equivalent to the minimal inhibitory concentration (MIC) and is defined as the concentration with incipient decrease in the extinction value (>=3%) at the end of the test period.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
In a standard bacterial test on cellular proliferation using the bacteria Pseudomonas putida (according to DIN 38412, part 8), no significant inhibitory effect was observed up to 100 mg/L of butyraldehyde following exposure for 16 hours.
Executive summary:

In a standard bacterial test on cellular proliferation using the bacteria Pseudomonas putida (according to DIN 38412, part 8), no significant inhibitory effect was observed up to 100 mg/L of butyraldehyde following exposure for 16 hours.