Registration Dossier
Registration Dossier
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EC number: 204-646-6 | CAS number: 123-72-8
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008-11-13
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Butyraldehyde
- EC Number:
- 204-646-6
- EC Name:
- Butyraldehyde
- Cas Number:
- 123-72-8
- Molecular formula:
- C4H8O
- IUPAC Name:
- butanal
- Details on test material:
- - Name of test material (as cited in study report): n-Butyraldehyde
- Substance type: organic
- Physical state: liquid
- Analytical purity: GC purity 99.7%
- Impurities (identity and concentrations): Iso-butyraldehyde: 0.05%, Butanoic acid: 0.10%
- Lot/batch No.:P9266
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 1.3
- Temp.:
- 20 °C
- pH:
- > 4.4 - < 4.7
- Details on results:
- Flask Log Pow
1:1 1.26
1:2 1.25
2:1 1.25
Any other information on results incl. tables
Analysed results with HPLC
Flask |
Water phase |
n-octanol phase |
1:1 |
0.028 mg/ml |
0.511 mg/ml |
1:2 |
0.018 mg/ml |
0.316 mg/ml |
2:1 |
0.029 mg/ml |
0.518mg/ml |
pH results
Flask |
pH in water phase |
1:1 |
4.7 |
1:2 |
4.6 |
2:1 |
4.4 |
Log Pow
Flask |
Log Pow |
1:1 |
1.26 |
1:2 |
1.25 |
2:1 |
1.25 |
Applicant's summary and conclusion
- Conclusions:
- Log Pow 1.3
- Executive summary:
Log Pow 1.3
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